Discuss a leg up.
Researchers say that taking a popular obesity medication and exercising often can result in weight reduction — and bone well being remains to be maintained.
Bone loss sometimes accompanies massive, speedy weight reduction, which will increase the danger of fractures. That is particularly a priority for older adults.
But the authors of a new Danish study discovered {that a} mixture of train and liraglutide preserves hip, backbone and forearm bone-mineral density. BMD is a measurement of calcium and different minerals in bone tissue.
Liraglutide alone reduces hip and backbone BMD in comparison with simply exercising, in accordance with the research.
“To our information, that is the primary research to evaluate the impact of [liraglutide] and train on bone well being each as separate therapies and together,” the researchers wrote of their findings, which have been published Tuesday in the journal JAMA Network Open.
Liraglutide — offered beneath the model names Victoza and Saxenda — is a part of a category of GLP-1 medicine that deal with weight problems and Sort 2 diabetes by lowering urge for food. Ozempic is part of this group.
Liraglutide has been previously shown to extend bone formation and stop bone loss in overweight ladies who’ve misplaced weight.
For this new research, 195 overweight contributors shed a minimum of 5% of their physique weight on an eight-week, very restrictive weight loss plan.
They have been then assigned to one in every of 4 yearlong packages — a reasonable to vigorous train routine, a each day dose of liraglutide, a mix of train and the drug, or a placebo injection.
The researchers discovered the train and liraglutide teams maintained the load loss, the mixture group shed further kilos, and the placebo group regained weight.
Regardless of the extra weight reduction, the mixture group was nonetheless in a position to protect bone well being.
There have been some limitations to the research — together with that the contributors didn’t produce other persistent ailments, so the outcomes might not translate to sufferers with diabetes or older individuals.
Nonetheless, the researchers say their “findings spotlight the significance of mixing train with [liraglutide] therapy for bone well being.”
