Weight loss surgery more effective than obesity drugs: study

Sorry, Ozempic customers.

Bariatric surgery results in extra weight reduction that’s longer-lasting in comparison with medication like Ozempic and Wegovy and behavioral modifications reminiscent of eating regimen and train, new research finds.

“Metabolic and bariatric surgical procedure stays the simplest and sturdy remedy for extreme weight problems. Sadly, it additionally stays among the many most underutilized,” stated research co-author and bariatric surgeon Dr. Marina Kurian of NYU Langone Well being.

Semaglutide medication like Ozempic and Wegovy mimic GLP-1 — the hormone the physique naturally produces after consuming — to make individuals really feel full, decreasing their cravings. AP

Researchers reviewed knowledge from roughly 20,000 weight reduction sufferers who participated in medical research and trials in the previous couple of years.

They discovered that weight problems medication and weight reduction surgical procedure proved far superior to eating regimen and train, which resulted in a median weight lack of 7.4% — these kilos have been usually regained inside 4 years.

Five months of weekly injections of semaglutide — the energetic ingredient in Ozempic and Wegovy — led to a weight lack of 10.6%. These medication mimic GLP-1 — the hormone the physique naturally produces after consuming — to make individuals really feel full, decreasing their cravings.

9 months of tirzepatide — offered beneath the model names Mounjaro and Zepbound — produced weight lack of 21.1%.

However the researchers discovered that after these remedies stopped, inside a yr, patients regained about half the load they’d misplaced.

Tirzepatide sufferers who continued with the injections tended to plateau at 17-18 months with 22.5% of their weight misplaced. Sufferers on semaglutide hit a roadblock at 14.9% weight reduction throughout the identical interval.

“Metabolic and bariatric surgical procedure stays the simplest and sturdy remedy for extreme weight problems. Sadly, it additionally stays among the many most underutilized,” stated research co-author and bariatric surgeon Dr. Marina Kurian of NYU Langone Well being. 96digital – inventory.adobe.com

Two fashionable surgical procedures, in the meantime, produced a weight reduction round 30% one yr after the operation. Sufferers maintained a 25% weight reduction as much as 10 years after surgical procedure, the researchers discovered.

“Surgical procedure must play a much bigger function in weight problems remedy and be thought of earlier within the illness course of,” Kurian added. “It’s now not a remedy of final resort and shouldn’t be withheld till extra extreme illness develops. There isn’t any medical cause for this.”

The analysis was introduced Tuesday on the American Society for Metabolic and Bariatric Surgical procedure (ASMBS) 2024 Annual Scientific Assembly.

The ASMBS reviews that nearly 280,000 weight loss procedures have been carried out within the US in 2022, representing solely about 1% of those that are eligible for them primarily based on their weight and peak.

Gastric bypass and sleeve gastrectomy are two sorts of weight reduction surgical procedures that scale back the scale of the abdomen. Some individuals could also be hesitant to go for surgical procedure as a result of restoration can take weeks.

There are potential drawbacks to weight problems meds as nicely, together with various unpleasant side effects. In a July 2023 survey, 4% of adults admitted to taking a prescription drug to drop a few pounds.

Weight problems impacts greater than 42% of Individuals, based on the Facilities for Illness Management and Prevention. BillionPhotos.com – inventory.adobe.com

All of the whereas, obesity rates continue to rise, affecting more than 42% of Americans, based on the Facilities for Illness Management and Prevention.

The intense situation has been proven to weaken the physique’s immune system, trigger continual irritation and enhance the chance of heart problems, stroke, Kind 2 diabetes, and sure cancers. 

A recent study warned that uncontrolled hypertension, diabetes and weight problems will result in at the very least six in 10 US adults being identified with heart problems throughout the subsequent 30 years.

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